Purpose

This pilot study utilizes a unique technology to determine nerve fiber sensitivity. This will allow us to determine whether this method and device can discern changes in pain intensity and type, which is predicated on differing nerve fiber sensitivities.

Condition

Eligibility

Eligible Ages
Between 18 Years and 65 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  1. The subject is 18 to 65 years of age 2. The subject is willing to have a tourniquet applied as part of the study 3. The subject is willing and able to provide written informed consent to the study participation 4. The subject is willing and able to comply with all study procedures

Exclusion Criteria

  1. Eye pathology precluding pupillometry 2. Subjects who have ongoing pain requiring medical attention 3. Subjects who are not normotensive 4. Subjects with peripheral vascular disease 5. Subjects who are morbidly obese (BMI >40) 6. Subjects with diabetes or diabetic retinopathy 7. Subjects who are or may be pregnant 8. Subjects with cardiac disease 9. Subjects with neuropathic disease states

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Recruiting Locations

More Details

NCT ID
NCT03596489
Status
Active, not recruiting
Sponsor
Julia Finkel

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.